
AccessClosure is a team of professionals sharing the passion and commitment to advance innovation within the field of access site management. Each member of our management team brings a great deal of experience within the medical field and a track record of success.
Gregory D. Casciaro
President & CEO

Gregory D. Casciaro has over 28 years of medical device experience, 23 of those years in the cardiovascular space and leadership positions in both public and private companies. Prior to joining AccessClosure, he was the President and CEO of XTENT Inc, (XTNT), a revolutionary drug-eluting stent platform. Prior to XTENT, Greg was the President and CEO of Orquest Inc., a private company manufacturing and selling bio-therapeutic products to the orthopedic market. Orquest was acquired by DePuy Acromed, a division of Johnson and Johnson. Prior to that, he was President and CEO of General Surgical Innovations (GSII) which was acquired by US Surgical, a division of Tyco (TYC). Greg has held several senior level positions with Devices for Vascular Intervention, a division of Guidant Corporation (GDT), and North American Instrument Corporation. In addition to his operating roles, Greg is on the Board of Directors for Trireme Medical Inc, and a former Director at Kerberos, acquired by FoxHollow Technologies, and a former Director with AngioDynamics (ANGO). Greg graduated from Marquette University in Milwaukee, WI with a B.A. in Business Administration.
John J. Buckley
Chief Financial Officer

Prior to joining AccessClosure, John J. Buckley was CFO at Acologix, Inc., a biotechnology company focused on osteo-renal diseases, where he was responsible for all finance and accounting functions, corporate planning, tax, treasury operation, corporate development and risk management. Prior to Acologix, John was a Partner with JWB Partners, CFO of The Dr. Spock Company and was with Ernst & Young LLP most recently as a Partner and as the Director of the Pacific Northwest Life Science Practice. John received his B.B.A. in accounting from the University of Wisconsin-Whitewater and is a Certified Public Accountant.
Susan Aloyan
Executive Vice President, Regulatory, Clinical and Quality Affairs

Susan Aloyan brings over 20 years of experience in domestic and international regulatory affairs to the AccessClosure executive team. Susan was previously the Vice President of Regulatory Affairs for Conceptus and helped bring numerous first in-category devices to market. Prior to joining Conceptus, Susan served as Corporate Director, Regulatory Affairs, Quality Assurance and Clinical Affairs with Gynecare/J&J. She was responsible for approval of the Essure permanent birth control device, as well as Gynecare’s ThermaChoice product. Susan also has been responsible for regulatory submissions at CardioGenesis Corporation and Syntex Corporation. Susan has a B.S. in Management from Golden Gate University and a M.A. in Organizational Management from University of Phoenix.
Ariel Sutton
Vice President, Marketing

Ariel Sutton joined AccessClosure in February 2008 as the Director of Market Development and brings over 10 years of marketing experience in the tech and medical device industries. During her tenure at AccessClosure, Ariel led the launch of the 5F Mynx Vascular Closure Device and the Mynx Cadence. Prior to joining AccessClosure, Ariel was the Director of Marketing at FoxHollow Technologies where she led both market development and product marketing. Prior to FoxHollow, she held engineering and marketing roles with Texas Instruments and LifeScan, a division of Johnson & Johnson. Ariel earned a Sc.B. in materials engineering from Brown University and a MBA from the Kellogg School of Management at Northwestern University.
Brian Armijo
Vice President, Operations

Prior to joining AccessClosure, Brian Armijo was the Vice President of Operations for Boston Scientific, Vascular Protection. There he was brought in at the early stages of the BSC acquisition of Embolic Protection, Inc. (EPI) where he successfully built and led the operations organization. Brian's previous roles in medical startups include: Director of Operations at Quanam Medical (through BSC acquisition), Director of Manufacturing at Somnus Medical, and finally Manager of Manufacturing at Arthrocare Corporation. Brian learned much of his craft through various technical leadership roles in the Manufacturing Management Program (MMP) at General Electric. He holds a dual degree from Brown University - a B.S. in electrical engineering-control systems and a B.A. in comparative literature, Spanish.
Andy Uchida
Vice President, Research and Development

Andy Uchida brings over 10 years of experience in medical device operations and research and development roles. Most recently, Andy was a Senior Director of Research and Development at FoxHollow Technologies where he and his team were responsible for the launch of several product line enhancements. Prior to joining FoxHollow, Andy was a Senior Manager of Research and Development at ORATEC Interventions in the spine products group. Prior to his medical device experience, Andy held systems engineering and research and development positions in the semiconductor and electronics industries. Andy holds a B.S. in mechanical engineering from California Polytechnic State University, San Luis Obispo and an MBA from University of California at Berkeley.
Sealant Science
The Mynx family of vascular closure devices represents a new approach to vascular closure by using targeted placement of the Mynx Sealant, which is composed of polyethylene glycol (PEG). PEG is a water-soluble, bio-inert, non-thrombogenic polymer known for its well-established safety profile and broad use in the medical field. PEG is used in products such as gel caps and cranial sealing (Duraseal™, Covidien).
The original Mynx Sealant consists of freeze-dried polyethylene glycol (PEG). Immediately upon placement of the Mynx Sealant on the arteriotomy, blood infiltrates the porous structure and the sealant expands to three to four times its size*. When fully expanded, the sealant consists of 95% blood and fluids and 5% PEG sealant.
As blood collects within the porous matrix, the coagulation produces a durable hemostasis and platform for natural vessel healing. Within 30 days, the sealant is absorbed by the body, leaving nothing behind but a healed artery.
Introducing Grip Technology: Grip Technology is a new configuration of the PEG sealant that actively grips the artery. When combined with the original Mynx Sealant, Grip Technology achieves active extravascular hemostasis, dissolving within 30 days and leaving nothing behind but a healed artery.
The MynxGrip Sealant is comprised of two configurations of polyethylene glycol (PEG), the Grip Tip and the original Mynx Sealant.
Grip Technology and the Grip Tip
The Grip Tip is a new configuration of PEG, developed using our proprietary Grip Technology, which allows the sealant to actively adhere to the artery wall.
Once the MynxGrip Sealant enters the tissue tract, the body’s temperature and pH level cause the Grip Tip to soften and interlock with the contours of the vessel wall, effectively gripping the artery and providing active closure.
Simultaneously, the porous structure of the Mynx Sealant absorbs blood and subcutaneous fluids, swelling three to four times its original size and filling the tissue tract.
The Result: A sealant that actively grips the artery while expanding and filling the tissue tract, providing a durable hemostasis and a platform for natural healing.
* Data on file with AccessClosure, Inc.
Ordering Information
The MynxGrip™ Vascular Closure Devices include:
(1) Balloon catheter with integrated sealant
(1) 10 ml locking syringe
| Size | Color | MynxGrip Order Number |
| 6F/7F | Green | MX6721 |
The Mynx Cadence™ Vascular Closure Device includes:
(1) Balloon catheter with integrated sealant
(1) 10 ml locking syringe
| Size | Color | Mynx Cadence Order Number |
| 6F/7F | Green | MX6701 |
| 5F | Gray | MX5001 |
The Mynx™ Vascular Closure Devices include:
(1) Balloon catheter with integrated sealant
(1) 10 ml locking syringe
| Size | Color | Mynx Order Number |
| 6F/7F | Green | MX6700 |
| 5F | Gray | MX5000 |
The Bengal™ Band includes:
(1) Compression bracelet
(1) Adaptor
(1) Sterile gauze pad
| Size | Bengal Order Number |
| Universal | RLXX01 |
In the United States, fax your order to AccessClosure at (877) 933-0133 or email to customerservice@accessclosure.com
Outside of the United States, contact your local Mynx distributor







